Uremia sounds scary… what is it?

Uremia is an accumulation of toxins and waste molecules. Think about it like your body’s garbage collector decided to take the month off (or the year, or the… you get it). Low GFR means that kidneys can no longer clean your blood properly. The waste has nowhere to go, so it settles and kicks its feet up while riding along your bloodstream. This is definitely not something you want because it causes:

Is advanced CKD a big deal?

YES! The disease can be life-threatening and has major affects quality of life. Advanced CKD is bad news for:

Heart failure
High blood pressure
Anemia
Acid and toxin buildup, which can trigger uremia (see below)
Blood potassium
Fluid retention
Low vitamin D
Abnormal electrolytes